In March, scientists discovered large amounts of antibodies against peanut allergens in the stomach and gut of allergic patients, according to the Genetic Literacy Project article. Dr. Cathryn Nagler, immunologist at the University of Chicago, discovered the allergic mice lacked the normal communication that takes place between gut microbes and immune cells. Honing in on the specific gut bacteria strains, her team found that Clostridia, but not Bacteroides, prevented food-allergic responses.
Another study led by Rima Rachid and Talal Chatila at Boston Children’s Hospital, found that the single species Subdoligranulum variabile and a set of Clostridia species, including Anaerostipes caccae, prevented allergic responses. In both studies regulatory T cells were key to the response with the microbes triggering the response. Researchers found that by adding healthy microbes to allergic mice showed results in preventing the allergic reactions in those mice.