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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

Gut bacteria triggers virus protecting response

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Gut bacteria triggers virus pro...
A November 19 2020 article in Genetic Engineering and Biotechnology News reported a study of mice by Harvard Medical School researchers who were able to pinpoint gut microbes that trigger an outer membrane (OM) polysaccharide A (PSA) of immune cell molecule that releases virus-repelling type 1 interferons. This discovery could help with drugs that boost antiviral immunity in humans.

According to the article the findings reveal that the protective response arises from immune cells residing in the walls of the colon. These dendritic cells release protective interferons when stimulated by the PSA molecule residing on the outer surface membrane of the Bacteroides fragilis gut bacterium.

The research identifies bacteroides fragilis, which is present in the gut of most humans, is triggering "immune cells in the colon to release interferon-ß (IFN-ß), an important immune chemical that confers antiviral protection," according to the report.

Taking the research a step further, the study found that the same antiviral triggering function exists in an entire class of microbial molecules. The research was led by Dennis Kasper, PhD, professor of immunology in the Blavatnik Institute at Harvard Medical School and first reported in Cell titled, “Commensal Microbiota Modulation of Natural Resistance to Virus Infection.”

https://www.genengnews.com/news/gut-bacteria-trigger-immune-defense-mechanisms-to-protect-against-viral-infections/

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