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HerbSprout Microbiome Blog -


Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community, alternative medicine, and Asian medicine, especially of China (TCM), India (Ayurveda), and Japan (eJim & Kampo).

Lactobacillus can help Japanese elderly gut health

The relationship between the intake frequencies of fermented milk products containing Lactocaseibacillus paracasei strain Shirota (LcS), according to the June 17 2021 report in Nature magazine, The gut microbiome of 218 Japanese subjects aged 66–91 years, some who consumed fermented milk over a year compared to a control group who did not. When ingested, LcS reaches the intestine alive and helps to ensure a good balance of gut microbiota among select elderly populations, says the study.

A 20-year study of Japanese in Gunma Prefecture reported the reduced risks of developing hypertension and infrequent bowel movements among elderly individuals who habitually take fermented milk products containing LcS. However, little remains known about the impact of the regular consumption of the probiotics, including LcS products, on the stability of human gut microbiota.

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C. Diff. bacteria treatment have positive results

A May 22 2021 article in MedPage Today reported two bacteria-based treatments for recurrent Clostridioides difficile infection that proved effective.

The studies tested proprietary mixtures of bacterial agents that colonize the intestinal tract and prevent C. difficile from thriving, and were reported on at the Digestive Disease Week (DDW) virtual meeting.

Though applied enema the treatment is different from the popularly known fecal transplant. Since fecal transplants involve a human donor, they are inherently variable.

Instead Rebiotix, unit of Ferring, applies RBX2660, a specific live bacteria that is delivered via enema. The other product, SER-109, is an oral mixture of Firmicutes bacterial spores, says Medpage Today article. Both showed varying degrees of success.

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Holobiome announces plans for psychobiotic human trials starting next year

Holobiome announces plans for...
According to a May 07 2021 report by the Association for the Advancement of Science announced in Science Magazine that the small startup company Holobiome plans to begin trials of human psychobiotic treatment for mental illnesses based on its research using human stool samples.

Holobiome CEO Phil Strandwitz believes microbe-based treatments or “psychobiotics, will offer solutions to mental illnesses and brain diseases. Strandwitz is working with microbiologist Katya Gravish to isolate gut bacteria strains that support mental health or have shown to alleviate mental illnesses from stool samples.

Tha Holobiome has stored one of the largest collections of human gut bacteria, according to the Science Magazine article. “We have in culture about 70%” of the known human gut microbes,” adds Strandwitz.

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