As reported in Medical Express’ July 28 2021 issue by Cornell’s David Nutt, Ilana Brito, Cornell assistant professor and the Mong Family Sesquicentennial Faculty Fellow in Biomedical Engineering in the College of Engineering, and her team took microbiome samples from the three global populations and put them in 30 germ-free mice to study immune responses to intestinal infections. Microbial differences among these populations proved to show the varying degrees of response. Researchers also found that “housing the mice together so that they shared microbiota helped mice with low resistance to infection become more resilient”, according to the Medical Express report. The less resilient mice benefited from the sharing of microbiota.
Brito and her team found that Guatemala microbiota proved most resistant, followed by the U.S., then Fiji, according to the Medical Express report where she is quoted, "The interesting thing was they are exhibiting these differences in resilience to infection in a very short time.” This points to a possible health remedy through sharing microbiota across regions of the world.