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HerbSprout Microbiome Blog -


Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

Urolithin A said to reduce aging

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According to Popular Science, researchers at the Swiss Federal Institute of Technology Lausanne (EPFL) and life-science company Amazentis believe they have found a way to reduce muscle decline and low energy with a highly pure Urolithin A supplement. Gut bacteria generate urolithin A from pomegranates, berries, and nuts.

Mitochondria which converts food into energy, generates adenosine triphosphate (ATP) life-sustaining chemical tissue, and mitophagy which is the process of breaking down old worn out mitochondria. The March 22 2022 Popular Science report says researchers found that Urolithin A boosts mitophagy. It is produced as a by-product when gut bacteria digest specific ingredients such as pomegranates (1).

David Marcinek, Ph.D., a professor of radiology at the University of Washington School of Medicine in Seattlein Medicine News Today, believes that Urolithin A supplements may provide a way to stimulate mitophagy in older people and help them maintain strength and endurance. He and his team are doing preliminary clinical trial to find out the efficacy and safety of such supplements (2).

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Gut microbiome linked to cognitive aging

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According to a February 22, 2022 Medical News Today report, researchers from the United States analyzed data from a large cross-sectional study of CARDIA, Coronary Artery Risk Development, in Young Adults and found a link between gut microbial composition and cognitive status in middle-aged adults.

607 stool samples were studied for DNA sequencing of adults across the country with a mean age of 55. The genera Barnesiella, Lachnospiraceae, and Akkermansia were positively associated with at least one of the cognitive tests, while Sutterella was negatively associated with one test.

Scientists believe that short-chain fatty acids play a part in regulating how the gut and brain interact. Short-chain fatty acids have been associated with protection against vascular dementia and cognitive impairment, according to the Medical News Today article.

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