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Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

Friendly gut bacteria show resilience after antibiotic treatment

Friendly gut bacteria show resi...
A new study reported January 18 2024 in Science Alert has found antibiotic resistance genes is giving our gut bacteria an ongoing advantage over microbes that cause us harm. They have beneficial effects “by promoting microbiome resilience to antimicrobials,” says University of Massachusetts bioinformatician Shakti Bhattarai (1).
In a study of 24 patients, Bhattarai and his team found that friendly bacteria reestablish strong presence in the gut following initial imbalance caused by antibiotics treatment.
Although antibiotic treatment severely destabilizes patient gut microbiota, repopulation of nonpathogenic bacteria between 6 to 24 months in the treatment, a process that was promoted by the emergence of mutated, antibiotic resistance in commensal species, adds original editor Catherine Charneski in Science (2)

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Gut microbial effects and Keto diet on epilepsy found

Gut microbial effects and Keto ...
It’s been known that diet creates some sort of shift in the gut’s microflora. Their functions in our digestive system influence a variety of neurological functions including those that influence epilepsy.
“The complexity of the brain, the hundreds of bacterial species that comprise the gut microbiome and the diversity of metabolites make it almost impossible to discern how bacteria impact brain function,” says Woo Kyu Kang, PhD, a postdoctoral fellow in the Alkema lab of UMass Chan Medical School, author of the current study.
In the study Kang, who worked with co-author Mark Alkema, fed diets of a single bacterial species, a mutant C. elegans, with their ability to produce vitamin B12. According to Dr. Alkema and Kang, vitamin B12 reduces the levels of choline in the body, a compound found in various foods that metabolizes fat in the liver, leading to increased seizures.
While C.elegans is believed to reduce epileptic side effects due to its vitamin B12 production, Bifidobacterium and Lactobacillus have been linked to positive effects on mood, stress, and cognitive function.
A mice study by lead authors, UCLA molecular biologist Gregory Lum and Elaine Hsiao, found that the keto diet; fat-rich, carbohydrate-poor diets somehow reduce the risk of seizures in those with refractory epilepsy, according to a January 02 2024 Science Alert report.

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プレバイオティクスとプロバイオティクスの共生。Prebiotic- probiotic symbiosis

source: dreamstime paid license. source: dreamstime paid license.
プロバイオティクスには腸の潜在的な水素(pH)を変化させ、免疫システムを高める力が あります。米国⻝品医薬品局(FDA)と世界保健機関(WHO)によると、プロバイオ ティクスは現在、「十分な量を摂取すると宿主に健康上の利益をもたらす生きた細菌」 と呼ばれています。 効果的なプレバイオティクスは、腸内微生物叢の構成を変化させ、有益な細菌の増殖を 促進しながら、有害な(病原性)細菌の増殖を阻害します。 プレバイオティクスには、結腸内の細菌の蔓延を促進し、人間の健康を改善することに より、有益な非消化性⻝品成分が含まれているとヒンダウィジャーナルが追加しまし た。「1」
プロバイオティクスは、人体のさまざまな領域に存在する特定の細菌種をサポートでき ます。プレバイオティクスは有益な微生物叢の拡大を促進し、プロバイオティクスの餌 として機能します。プロバイオティクスは、「結腸内のカルシウムやマグネシウムなど のたくさんのミネラル、発酵の副産物としての短鎖脂肪酸(SCFA)や乳酸の生成、そ して宿主の免疫システム」をサポートします。
物理的および化学的な変動があり、さまざまな肌タイプで多様な微生物叢組成を作り出 します。しかし、2022年11月のヒンダウィ報告書によると、放線菌、バクテロイデス 属、シアノバクテリア、ファーミクテス属、およびプロテオバクテリアが皮膚微生物叢 の大部分を占めているとのことです。「1」

Probiotics and prebiotics maintain a symbiotic relationship. For example, Prebiotics enhance probiotics like Lactobacilli and Bifidobacteria in quantity and activity.
Probiotics have the ability to alter gut pH and boost the immune system. Probiotics are currently referred to as “living bacteria that, when eaten in sufficient numbers, provide the host with health benefits” according to both the Food and Drug Administration (FDA) and the World Health Organization (WHO).
Effective prebiotics can change the composition of the gut microbiota, encouraging the growth of helpful bacteria while inhibiting the growth of harmful (pathogenic) ones.
Prebiotics have beneficial non-digestive food components by promoting the prevalence of bacteria in the colon, improving human health, adds the Hindawi report.
Probiotics can support specific bacteria species present in different regions of the human body. Prebiotics encourage the expansion of beneficial microflora, serving as food for the probiotics. They support “the amount of minerals in the colon, such as calcium and magnesium, creating short-chain fatty acids (SCFA) and lactic acid as a byproduct of fermentation, and the host immune system”.
Hindawi reports that Firmicutes, Proteobacteria, Bacteroidetes, Actinobacteria, and Fusobacteria are the most prevalent bacteria in the oral microbiota. Although it was once thought that human lungs in good health were sterile, multiple studies have shown that bacteria can also be found in lung tissues. These lung Microbiota include Actinobacteria, Bacteroidetes, Firmicutes, and Proteobacteria.
There are physical and chemical variations creating diverse microbiota compositions in various skin types. However, Actinobacteria, Bacteroidetes, Cyanobacteria, Firmicutes, and Proteobacteria make up the majority of the skin microbiota, according to the November 2022 Hindawi report.

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