Nacalai USA's Blog

"Simultaneous Separation and Identification of All Structural Isomers and Enantiomers of Aminobutyric Acid Using a Highly Sensitive Chiral Resolution Labeling Reagent" was published in Analytical Methods (2023).
https://doi.org/10.1248/cpb.c23-00439

The following products were used in this study.
* DL-Amino Acid Labeling Kit
* COSMOSIL PBr packed column

"Separation and Identification of Isoleucine Enantiomers and Diastereomers Using
an Original Chiral Resolution Labeling Reagent" was published in Chemical and Pharmaceutical Bulletin Advance Publication in August 24, 2023
https://doi.org/10.1248/cpb.c23-00439

The following products were used in this study.
* DL-Amino Acid Labeling Kit
* COSMOSIL PBr packed column
* COSMOSIL piNAP packed column

We are pleased to announce that the study using our DL-amino acid labeling kit, made in collaboration with Professor Hideaki Kakeya from Graduate School of Pharmaceutical Sciences, Kyoto University, was selected for inclusion in HOT Articles 2023 by the Royal Society of Chemistry journal Analyst.

Press Release: Separation of amyloid β fragment peptides using DL-Amino Acid Labeling Kit (2/8/2023)

Product Information: DL-Amino Acid Labeling Kit

We are pleased to announce that the study using our DL-amino acid labeling kit, made in collaboration with Professor Hideaki Kakeya from Graduate School of Pharmaceutical Sciences, Kyoto University, was selected for inclusion in HOT Articles 2023 by the Royal Society of Chemistry journal Analyst, 2023, Advance Article

We will be attending the PITTCON 2023, booth No. 2744, March 20-22, Philadelphia, Pennsylvania.
https://pittcon.org/pittcon-2023/

One of our customers has succeeded in separating delta-9-THC enantiomers using our CHiRAL 5A column.
https://www.nacalaiusa.com/products/view/355/cosmosil-chiral-series
https://www.nacalaiusa.com/products/view/407/application-cannabinoids-analysis

Cannabinoids of various types have recently become compounds of interest with the potential to treat various ailments. As many of these compounds have optical isomers, separation these enantiomers could prove to be important to research into their therapeutic potential.

"Separation and identification of the DL-forms of short-chain peptides using a new chiral resolution labeling reagent" was published in Anal Bioanal Chem on 06 April 2022.
https://doi.org/10.1007/s00216-022-04048-w


The following products were used in this study.

*** DL-Amino Acid Labeling Kit ***
https://www.nacalaiusa.com/products/view/528/dl-amino-acid-labeling-kit

*** COSMOCORE 2.6C18 packed column ***
https://www.nacalaiusa.com/products/view/235/cosmocore-2-6c-sub-18-sub

*** COSMOCORE 2.6Cholester packed column***
https://www.nacalaiusa.com/products/view/254/cosmocore-2-6cholester

*** COSMOSIL 3PBr packed column ***
https://www.nacalaiusa.com/products/view/238/cosmosil-pbr

*** COSMOSIL CHiRAL 3C packed column ***
https://www.nacalaiusa.com/products/list/71/chiral-separation-columns

Please click link below to view application data using DL-Amino Acid Labeling Kit.
https://www.nacalai.co.jp/cosmosil/data/csmosrchlst.cfm?UpdDate=20210930000000&NameKey=&NameSrch=2&CASNo=&MultiClassify=01&RyuKei=0&AppNo=&kensu=20&lc=E

ex. D-DLDA-DL-Amino Acids
https://www.nacalai.co.jp/cosmosil/data/png/AP/AP-1844.png

This product is an amino acid labeling kit for HPLC analysis. Due to their high polarity and insufficient UV absorbance, amino acids need to be labeled prior to HPLC. In addition, research on D-amino acids has recently been gaining prominence. With conventional labeling reagents, such as phenyl isothiocyanate and dansyl chloride, costly chiral columns are required. This product is designed to label amino acids without intensive labor and achieve chiral separation with achiral columns, such as C18.

Please click the link below to find more information:
https://www.nacalaiusa.com/products/view/528/dl-amino-acid-labeling-kit