Search Bloguru posts

Nacalai USA's Blog

https://en.bloguru.com/nacalaiusa
  • Hashtag "#lcms" returned 7 results.

PITTCON 2024: Booth# 2924

thread
PITTCON 2024: Booth# 2924
We will be attending the PITTCON 2024, booth No. 2924, February 26-28, San Diego, CA.
#c18 #drug #exhibition #hplc #lcms

People Who Wowed This Post

* 20% OFF * Exclusive Online Discount on COSMOSIL Special Columns

thread
* 20% OFF * Exclusive Online ...
For a limited time, we are offering a special promotion on COSMOSIL Cholseter, PBr, PFP, piNAP, and PYE columns. You can now purchase 4.6 x 150 mm and 250 mm columns at a 20% discount from the listed price by using the promo code PITTCON24.
 
 
 
 
 
 
 
*** PromoCode: PITTCON24 ***
*** Valid until 03/31/2024 ***
 
 
The discount will be:
- applied only to the columns listed on our website.
- not available to overseas.
- cannot be combined with any other offer, promotion or discount.
#drug #hplc #iosmer #lcms #screening #specialoffer

People Who Wowed This Post

Simultaneous Separation and Identification of All Structural Isomers and Enantiomers of Aminobutyric Acid.

thread
Simultaneous Separation and Id...
#aminoacid #chiral #drug #hplc #isomer #labeling #lcms #reference

People Who Wowed This Post

ASMS 2024 : Booth No. 260

thread
ASMS2024 at Anaheim, CA ASMS2024 at Anaheim, CA
We are attending the ASMS 2024 Annual Conference, booth No. 260. June 2-6, Anaheim, CA.
#analytical #asms #exhibition #hplc #lcms #mass

People Who Wowed This Post

Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column

thread
Separation of highly hydrophili...
We published "Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column" in MethodsX, 2023, 10. 102061.

DOI: https://doi.org/10.1016/j.mex.2023.102061

Abstract: 
Highly hydrophilic compounds such as nicotinamide metabolites are very difficult to separate via high-performance liquid chromatography (HPLC) using octadecyl (C18) columns. In general, for the separation of hydrophilic compounds, hydrophilic interaction liquid chromatography (HILIC) columns are used instead of reversed phase chromatography using C18 columns. However, HILIC columns generally obey complex separation mechanisms because ionic interactions are involved in the retention process, which hinders the optimization of the separation conditions. Additionally, the resulting peak shapes are disturbed when large amounts of aqueous samples are injected. This study demonstrates that COSMOSIL PBr columns, in which both hydrophobic and dispersive interactions occur, show high retention for various hydrophilic compounds under similar separation conditions as those used with C18 columns. Specifically, using a COSMOSIL PBr column, 11 nicotinamide metabolites could be separated under simpler conditions than those used previously with C18 columns, affording better peak shape for each compound. The applicability of the method was evaluated using a tomato sample, from which the nicotinamide metabolites were successfully separated. The results show that the COSMOSIL PBr column is a good alternative to the C18 column for a good separation of all the peaks, including impurity peaks.



The following products were used in this study.
COSMOSIL PBr Packed Column
#NMN #hilic #hplc #lcms #nicotinamide #reference

People Who Wowed This Post

COSMOSIL® Application(HPLC / UHPLC / SFC)

thread
COSMOSIL® Appli...
COSMOSIL Application, which includes more than 7,900 applications using COSMOSIL columns, is now available. The application is searchable by sample category, sample name, CAS RN., column name and particle size.

*** Only show new applications added since September 2021
https://www.nacalai.co.jp/cosmosil/data/csmosrchlst.cfm?UpdDate=20210930000000&NameKey=&NameSrch=2&CASNo=&RyuKei=0&AppNo=&kensu=20&lc=E

*** Only show applications using SFC columns
https://www.nacalai.co.jp/cosmosil/data/csmosrchlst.cfm?SFC_Check=SFC&NameKey=&NameSrch=2&CASNo=&RyuKei=0&AppNo=&kensu=20&lc=E
#application #data #hplc #lcms

People Who Wowed This Post

Reference: New amino-acid labeling reagent, (D)FDLDA

thread
Reference: New amino-acid lab...
"Separation and identification of the DL-forms of short-chain peptides using a new chiral resolution labeling reagent" was published in Anal Bioanal Chem on 06 April 2022.
https://doi.org/10.1007/s00216-022-04048-w


The following products were used in this study.

*** DL-Amino Acid Labeling Kit ***
https://www.nacalaiusa.com/products/view/528/dl-amino-acid-labeling-kit

*** COSMOCORE 2.6C18 packed column ***
https://www.nacalaiusa.com/products/view/235/cosmocore-2-6c-sub-18-sub

*** COSMOCORE 2.6Cholester packed column***
https://www.nacalaiusa.com/products/view/254/cosmocore-2-6cholester

*** COSMOSIL 3PBr packed column ***
https://www.nacalaiusa.com/products/view/238/cosmosil-pbr

*** COSMOSIL CHiRAL 3C packed column ***
https://www.nacalaiusa.com/products/list/71/chiral-separation-columns
#Chiral #HPLC #LCMS #aminoacids #peptides #reference

People Who Wowed This Post

  • If you are a bloguru member, please login.
    Login
  • If you are not a bloguru member, you may request a free account here:
    Request Account
Happy
Sad
Surprise