"We are running out of antibiotics"
Dec
5
"We are running out of antibiotics," says Kim Lewis, who directs the Antimicrobial Discovery Center at Northeastern, where the discovery of darobactin was made. "We need to be looking for novel compounds with no pre-existing resistance in the clinic or the population."
Yu Imai, a postdoctoral research associate in Lewis' lab, discovered the compound from Photorhabdus bacteria that live inside the gut of a nematode, a tiny parasitic worm found in soil. It's the first time, Lewis says, that the animal microbiome was found to harbor an antibiotic that promises to be useful for humans.
For more information, see https://phys.org/news/2019-11-antibiotic-gut-tiny-worm-weapon.amp
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