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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

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  • How Gut Microbiota Contributes to Depression

How Gut Microbiota Contributes to Depression

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How Gut Microbiota Contributes...
The gut microbiota is thought to influence MDD (major depressive disorder) through inflammatory processes, primarily in the gut-brain axis. A December 13, 2019 article by Psychiatry Advisor and the European Journal of Neuroscience, says "mice treated with the probiotic Bifidobacterium adolescentis showed a reversal of neuroinflammation and depressive symptoms." Gut bacteria are essential to communication between the gut and the brain, and helps to regulate brain development and function. See article for more information at https://www.psychiatryadvisor.com/home/depression-advisor/gut-microbiota-can-drive-neuroinflammation-in-major-depressive-disorder/ .

Experimental evidence links changes in the chemokine network to depressive behavior, and researchers of clinical studies indicated an association between neuroinflammation and MDD, according to the report. This and other similar results of studies have generated increased interest in the use of anti-inflammatory microbiome agents in the treatment of MDD. Another article by Nature Microbiology found two types of bacteria, Coprococcus and Dialister, which are depleted in people with depression. Researchers reported this in a February 4, 2019 in Nature Microbiology article.

Other studies suggest that certain probiotics can serve as effective antidepressants. 34 controlled clinical trials, led by researchers from the Department of Psychiatry and Human Behavior at the Warren Alpert Medical School at Brown University (Rhode Island, USA) came to this conclusion. Of the 34 clinical trials, 27 interventions were probiotic and 7 were prebiotic, including Bifidobacterium longum, Bacillus coagulans, and Lactobacillus alone or in combination with Bifidobacterium. Each demonstrated anti-anxiety and/or anti-depressant effects. See the following article published June 04, 2019 at https://www.gutmicrobiotaforhealth.com/en/a-new-meta-analysis-of-controlled-clinical-trials-shows-the-antidepressant-and-anxiolytic-potential-of-probiotics/ .

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