Gut bacteria triggers virus protecting response
Dec
6
According to the article the findings reveal that the protective response arises from immune cells residing in the walls of the colon. These dendritic cells release protective interferons when stimulated by the PSA molecule residing on the outer surface membrane of the Bacteroides fragilis gut bacterium.
The research identifies bacteroides fragilis, which is present in the gut of most humans, is triggering "immune cells in the colon to release interferon-ß (IFN-ß), an important immune chemical that confers antiviral protection," according to the report.
Taking the research a step further, the study found that the same antiviral triggering function exists in an entire class of microbial molecules. The research was led by Dennis Kasper, PhD, professor of immunology in the Blavatnik Institute at Harvard Medical School and first reported in Cell titled, “Commensal Microbiota Modulation of Natural Resistance to Virus Infection.”
https://www.genengnews.com/news/gut-bacteria-trigger-immune-defense-mechanisms-to-protect-against-viral-infections/