Search Bloguru posts


Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

MS prevention at the microbiome source

MS prevention at the microbio...
Major breakthroughs seem to accelerate as more energy is dedicated to research in a field. This is true of gut microbiome research. Multiple Sclerosis is debilitating disease where our own immune system causes nerve damage by eating away at the protective covering of nerves.

Scientists at the University of Virginia (UVA) sought to find out what attacks the sheaths around nerves in the brain causing Multiple Sclerosis (MS). They found that the inflammation-causing mechanism could be turned off at its source, in the gut microbiome, according to a February 16 2023 report in New Atlas. This is a new approach to potentially treating multiple sclerosis, says Andrea Merchak, neuroscience doctoral candidate at UVA and lead author of the study.

Researchers in 2021 found that inhibiting a protein called Piezo1 produced by T-cells could allow the cells to decrease inflammation in mouse models.

Building on the 2021 work, the University of Virginia researchers targeted the regulator of inflammation-causing aryl hydrocarbon receptor (AHR). AHR is produced by T-cells, a type of white blood cell that battles invaders to the body. When the researchers blocked it in the guts of mice, they found that the microbiome was able to produce compounds such as bile salts and short-chain fatty acids that made it difficult for the T-cells to thrive, and decrease the inflammation in mice leading to MS.

People Who Wowed This Post

  • If you are a bloguru member, please login.
  • If you are not a bloguru member, you may request a free account here:
    Request Account
* indicates required fields
  • Comments must be approved before they are displayed

🙂 Using emojis in your blog:
• Keyboard shortcuts: For Mac, press [Ctrl + Cmd + Space]; for Windows, press [ Windows Key + . ]
• Copy and paste: Find a list of emojis and paste them into the text field.
  • none
  • center
  • left
  • right
If checked, your avatar will be displayed