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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

Another potential disease prevention tied to gut microbiome and SCFAs

Oct
17
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Another potential disease preve...
A September 30 2020 Genetic Engineering and Biotechnology News article reported that Keio University School of Medicine's Dr. Hitoshi Tsugawa may have found a new approach to disease prevention. Tsugawa's study of mice demonstrated interaction between an immune cell protein, short-chain fatty acids (SCFAs), and gastrointestinal bacteria in our gut. The interaction triggers protection against Salmonella infection.

Some of the gut microbial species inside our gut can break down fiber eaten as part of the diet into short-chain fatty acids, which protect against the potential infections such as Shigella, E. Colin, and Salmonella, the report said. The study also examined how SCFA receptors contribute to the regulation of innate immune responses.

Tsugawa's team found that the SCFAs could bind to a protein called apoptosis-associated speck-like protein (ASC) to, prevent the inflammatory process. ASC is part of an inflammasome complex, which helps to activate the inflammatory response.

https://www.genengnews.com/news/dietary-fiber-gut-microbiome-and-immune-cells-work-together-to-prevent-infection/
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