Another potential disease prevention tied to gut microbiome and SCFAs
Oct
17
Some of the gut microbial species inside our gut can break down fiber eaten as part of the diet into short-chain fatty acids, which protect against the potential infections such as Shigella, E. Colin, and Salmonella, the report said. The study also examined how SCFA receptors contribute to the regulation of innate immune responses.
Tsugawa's team found that the SCFAs could bind to a protein called apoptosis-associated speck-like protein (ASC) to, prevent the inflammatory process. ASC is part of an inflammasome complex, which helps to activate the inflammatory response.
https://www.genengnews.com/news/dietary-fiber-gut-microbiome-and-immune-cells-work-together-to-prevent-infection/
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