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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community, alternative medicine, and Asian medicine, especially of China (TCM), India (Ayurveda), and Japan (eJim & Kampo).

Gut Dysbiosis an early cue to onset of brain diseases; 腸内毒素症は脳疾患の発症への初期の糸口

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source: shutterstock.com source: shutterstock.com
Evidence continues to shows the gut microbiome is altered early in both Parkinson's, dementia and Multiple Sclerosis patients, according to a November 10 2020 article in the Conversation.

Parkinson’s disease gut dysbiosis, often as constipation or diarrhea, is common. Gut problems may be present several decades before typical symptoms appear, according to the article.

Research has shown gut microbes appear to play a key role in sending and receiving the signals to and from the brain, such as stress signals. One way microbes do this is they produce proteins that carry messages to the brain. Another way is through the vegus nerve which physically connects the brain to the gut.

While this communication for the most part is generally healthy and benign, unhealthy microbiome can transmit harmful pathogens and abnormal proteins to the brain when the gut microbiome is in a state of dysbiosis. Studies show this can lead to a number of brain diseases such as Parkinson's, Alzheimer's, Huntington's, Multiple Sclerosis (MS), and dementia.

The gut microbiome plays a critical role beyond being an indicator. Another study by the University of California San Francisco found that "immune cells produced in the gut play a protective role during multiple sclerosis (MS) flare-ups," according to a November 22 2020 article by the New Atlas. Scientists demonstrated how these immune cells "travel up to the brain and potentially help shift a disease flare-up into remission."

While more research is needed in this field, a change in diet, a diet rich in fiber, or consumption of probiotics can potentially prove to be an effective remedy for patients experiencing the onset of dysbiosis.

https://theconversation.com/amp/your-gut-microbiome-may-be-linked-to-dementia-parkinsons-disease-and-ms-144367

https://newatlas.com/health-wellbeing/immune-gut-brain-mechanism-multiple-sclerosis-ms-flare-up/

Other related stories:

http://www.global-engage.com/life-science/gut-brain-axis-insights-why-the-microbiota-holds-therapeutic-potential-for-neuro-developmental-disorders/

https://en.bloguru.com/healthtech/373012/need-more-proof-our-gut-bacteria

https://en.bloguru.com/healthtech/371304/gut-bacteria-strains-found-to-prevent

https://en.bloguru.com/healthtech/377424/evidence-of-lactate-producing-gut

https://www.statnews.com/2020/11/20/multiple-sclerosis-gut-microbiome-link/

腸内毒素症は脳疾患の発症への初期の糸口

2020年11月10日の記事の会話によると、パーキンソン病、認知症、及び多発性硬化症の両方の患者の腸内細菌叢が早期に変化している証拠が引き続き示されています。

パーキンソン病の腸内毒素症は、しばしば便秘や下痢としてよく見られます。記事によると、腸内の問題は、典型的な症状が現れる数十年前に存在する可能性があります。

研究によると、腸内微生物は、ストレス信号など、脳との間の信号の送受信に重要な役割を果たしているようです。微生物がこれを行う1つの方法は、脳にメッセージを運ぶタンパク質を生成することです。脳を腸に物理的に接続する迷走神経を通すことは別の方法です。

このコミュニケーションの大部分は一般的に健康で良性ですが、腸内細菌叢が腸内毒素症の状態になっている時に、不健康な微生物が有害な病原体や異常なタンパク質を脳に感染させる可能性があります。研究によると、これはパーキンソン病、アルツハイマー病、ハンチントン病、多発性硬化症(MS)、認知症など、多くの脳疾患につながる可能性があります。

この分野ではさらなる研究が必要ですが、食物繊維が豊富な食事療法に変更したり、プロバイオティクスを消費したりすることで、腸内毒素症の発症を経験している患者にとって効果的な治療法であることが潜在的に証明される可能性があります

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