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HerbSprout Microbiome Blog -

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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations, and our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community, alternative medicine, and Asian medicine, especially of China (TCM), India (Ayurveda), and Japan (eJim & Kampo).

How gut microbiome interact with prescription drugs

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source: dreamstime.com source: dreamstime.com
A June 10 2020 article in SciTech Daily explains "how gut bacteria metabolize drugs, and could aid the development of medications that are more effective, have fewer side effects, and are personalized to an individual’s microbiome". The research was conducted by researchers at Princeton University and led by Mohamed S. Donia, assistant professor of molecular biology.

The researchers identified 57 cases in which gut bacteria can alter existing oral medications, which can alter the medications to be less effective, not effective at all, or even toxic. Unfortunately, the Princeton study will require more detailed study of specific gut microbiome strains to isolate which bacteria are affecting the medications and how.

The SciTech Daily reported that "researchers found that some people’s microbiomes had little effect on a given drug, while other microbiomes had a significant effect," causing a wide variability between individuals tested. In addition, Princeton's Donia said it calls for studying of various drugs on the "entire intestinal microbial community.”

https://scitechdaily.com/princeton-researchers-catalog-the-gut-microbiomes-impact-on-medications/amp/

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