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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

"One man's food is another man's poison"

Jun
20
thread
Naveen Jain, CEO, Viome. Naveen Jain, CEO, Viome.
What if? What if our current understanding of microbiomes is not ‘what if’, but ‘what is’? Because today, our understanding of healthcare has gone full circle to the conclusion that “there is no such thing as a universal healthy diet.” There is no universal healthcare solution, since every person is different down to the molecular level. Naveen Jain, CEO of Viome adds, “a diet that’s good for you, is not good for me. A diet that's good for me now won't be good for me three months from now because our microbiomes are constantly changing,” he says. “Our microbiomes to some extent controls our brain through the way they are constantly communicating with it back and forth. In fact, these bugs in our gut are like a puppet master. They tell our brain when we are hungry, they tell us what we crave. So when you crave chocolate, don't blame your brain, blame your microbiomes.”

“The interesting thing is they communicate with the micro RNA in your brain in the amygdala and prefrontal cortex. That means they (contribute to) controlling our emotional behavior and they (contribute to) controlling our decision making. They in fact modify the genetic expression of our human genes. That means it's not even what our DNA tells us. Our DNA is simply a potential of what could happen. Our genetic expression tells you actually what is happening and these guys (microbiomes) control what is actually being expressed.”

“It's really to some extent what Hypocrates stated, ‘all diseases start in the gut.’ That was two thousand years ago. ‘One man's food is another man's poison. And that is true today.’ So when your mother says to you ‘listen to your gut; do your gut check.’ That is the best science advice you can get. She knows what she is talking about.”

Referring to Viome’s transcriptome testing technology, “The technology is able to look at every single thing that's happening in the body. What genes are being expressed by your mitochondria; What genes are being expressed by your blood; What genes are being expressed by your microbiome; And it looks at all of that with artificial intelligence and tells you exactly what food to eat and what food to avoid.”

From a small stool sample, Viome is able to do this. It is able to perform a complete sequencing and identify the strain and genetics expression of a person’s entire microbiome content. This includes all the person’s bacteria, viruses, bacteriophages, archaea, fungi, yeast, and parasites, and the range of chemicals, or metabolites they create. The metabolites these microbiomes create are important to one’s health because they can produce healthy B vitamins, for example, or they can produce cancer causing agents. No other company can claim this breadth of data.

To find out more information, visit http://Viome.com .
#ai #bacteria #cardiovasculardisease #datascience #gutmicrobiome #health #healthinnovation #healthtech #obesity

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What is butyrate, and why are they so very important?

Jun
17
thread
Here is one of the "symbiotic" relationships we have with the bacteria in our gut. There are three main short chain fatty acids (SCFA) - acetate, propionate, and butyrate - that are produced by our gut microbiome. Butyrate is a byproduct of your gut microflora breaking down prebiotic fibers and serve as food for the cells that line the walls of our gut. When we consume prebiotic foods, our gut bacteria ingests these foods and produce the short chain fatty acids (SCFA). It has been linked to health benefits such as reduced cancer risk, weight loss, reduction in hypercholesterolemia, improved electrolyte/mineral absorption and a healthier immune system.

Some good butyrate sources to include in your diet would be beans, muesli, cooked plantains, unripe bananas, cooked potatoes and cooked rice, as they upregulate the production of butyrate in your body. On the other hand, butter and ghee are directly ingested sources of butyrate and thus highly recommended for use in cooking!

More reading about the benefits of butyrate:
https://www.fivejourneys.com/blog/tackling-gut-health-with-sources-of-butyrate-why-what-how/

https://atlasbiomed.com/blog/what-is-butyrate/

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Gut microbiome discovery bring new meaning to "follow your nose"

Jun
13
thread
Gut microbiome discovery brin... Gut microbiome discovery brin...
A May 31 2020 study by University of Antwerp, Belgium reported hy Science Alert brings new meaning to the Fruit Loops Toucan famous saying, "follow your nose, it always knows."

University of Antwerp microbiologist Sarah Lebeer and her team analysed nose bacteria from 100 healthy volunteers and 225 people with chronic rhinosinusitis, a condition of swelling and pain in the nasal passages. They found that lactobacilli, particularly Lacticaseibacillus, were abundant up to 10x more in healthy participants.

See article here, https://www.sciencealert.com/your-nose-bacteria-might-play-a-role-in-good-health-just-like-the-gut-microbiome/amp .
#ai #bacteria #cardiovasculardisease #datascience #gutmicrobiome #health #healthinnovation #healthtech

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Keystone Species "key" to healthy gut

Jun
10
thread
Keystone Species "key" to heal... Keystone Species "key" to heal...
Just as keystone species in wildlife are important for a healthy ecosystem, the same is true of the microbiota in our gut. Probiotics are the foundation for gut health and overall immunity, according to Jenny Pandol, Executive Director of the Microbiome Learning Center.

"We need certain strains of bacteria to modulate the gut. While it’s true we need to be taking high quality probiotics and perhaps many OTC may be ineffective, the opposite is true with quality probiotics added to the diet along with other lifestyle and diet modifications."

"There are certainly trusted brands and yes, the gut Microbiome can change day to day and even meal to meal," says Pandol..

"The key is to have balance with certain keystone species that modulate the ecosystem. They are like body guards keeping things in check and keeping pathogenic organisms from over growth. Different microbes thrive on different fibers so depending on what you eat certain microbes will thrive."

The following gut bacteria are among the keystone species we need for a healthy gut: Bifidobacteria, Akkermansia, christendsenella, clostridia, bacillus subtilis species. We need Lacto but they aren’t considered keystone, adds Pandol.

There a few quality probiotic supplement brands that stand out in quality, among others. These are Terra flora , Megaspore, Designs for Health, Metagenics to name a few.

More information about the Microbiome Learning Center is available here: https://microbiomelearningcenter.com

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Microbiome is everywhere in wildlife from fish to honey bees

Jun
6
thread
Microbiome is everywhere in w... Source: Adobe stock images Source: Adobe stock images
A May 11 2020 article by Phys.org suggests that healthier fish from the fish farm industry which makes up almost half of what we eat (45%) begins with healthier gut bacteria in the fish. Research on "fish guts" is led by the aquaculture or fish farming industry to bring benefits to consumers; healthier fish, cheaper but higher quality produce, according to the Phys.org report (1).

Reseachers are applying and testing the effects of alternative plant and insect based proteins to feed fish. These have different effects on the fish gut microbiome, and ultimately their health.

Gut microbiome populations exist in almost everything we consume, from fish and red meat to honey. Social bees collect microbes like Bifidobacterium from feeding on fermenting honey, according to an April 14 2020 study by University of Washington candidate Lila Westreich (2). She wrote about this in The Conversation. Westreich found that social bees collect microbes like Bifidobacterium from feeding on fermenting honey, according to the article (2). Research published in Plos One found 13 lactic acid bacteria that inoculate and preserve pollen in the hives. These include Lactobacillus kunkeei, and Alpha 2.2 (Acetobacteraceae), found in stored pollen and honey (3).

Sources:
1 https://phys.org/news/2020-05-healthy-gut-microbiomes-farmed-fish.html ;
2 https://theconversation.com/amp/bees-seeking-bacteria-how-bees-find-their-microbiome-129534 ; and
3 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095056
#bacteria #datascience #diet #gutmicrobiome #health #healthinnovation #healthtech #herbalmedicine #herbs #mentalhealth #plantnutrition #probiotics

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Ketogenic diet affects your health by changing gut microbiome

Jun
3
thread
Ketogenic diet affects your heal...
It is believed that the ketogenic diet lowers inflammation in our bodies, may treat autoimmune disorders, and promotes weight loss and heart health, according to a May 20 2020 article by Medical Express. The goal of ketogenic diet is to reach a state of ketosis where a lower carb intake leads the body to break down stored fat for energy.

Based on studies of both humans and mice, ketogenic diets dramatically reduced the common probiotic Bifidobacteria. However, the studies also found that the ketogenic diet reduces the gut microbial content of phyla Actinobacteria, Bacteroidetes, and Firmicutes, and 19 different bacterial genera. The studies were led by Peter Turnbaugh, Ph.D., a University of California San Francisco associate professor of microbiology and immunology, and a member of the UCSF Benioff Center for Microbiome Medicine.

With the lower level of carb intake, based on studies of mice, a ketogenic diet may lead to some of the effects of ketosis quite quickly. Ketosis is not necessarily good for you as acidic byproducts can build up in our bodies called ketoacidosis.

See Medical Express article here, https://medicalxpress.com/news/2020-05-ketogenic-diets-gut-microbiome-humans.amp . The article was first reported in the Cell, https://www.cell.com/cell/pdf/S0092-8674(20)30490-6.pdf
#ai #bacteria #cardiovasculardisease #datascience #gutmicrobiome #health #healthinnovation #healthtech #ketogenicdiet #obesity

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Ginseng & Ginger are two healthy TCMs during stressful times

May
30
thread
Source: getty images Source: getty images Ginseng & Ginger are tw...
A May 17 2020 article by Yahoo News suggests you might consider incorporating some traditional Chinese medicine (TCM) ideas into your daily practice. There's much to choose from- qi gong, acupressure/ acupuncture, teas and tonics, and food. Yahoo News recommended these TCM remedies in this order.

Given that food and teas are more prevalent and widely used, let's look at it from the opposite order. Beginning with the universally accepted herb ginger, which contains Gingerol. Regular consumption of it couldn't hurt. Gingerol is the main bioactive compound in ginger that is anti-inflammatory and a digestive aid. This is based on studies referenced by the Healthline article below.

Ginseng has also been tested and proven to boost the immune system with its bioactive compounds, ginsenosides and gintonin, according to WebMD. Regarding both ginger and ginseng, there have been broad but varying unproven claims that these food based herbs provide other benefits such as lowering blood sugar and treating cancer. However, consuming them in moderation can help and is recommended.

For more information see: https://news.yahoo.com/amphtml/try-traditional-chinese-medicine-practices-214001491.html ; and
https://www.healthline.com/nutrition/ginseng-benefits#section1
#ai #bacteria #datascience #diet #gutmicrobiome #health #healthinnovation #healthtech #herbalmedicine #herbs #mentalhealth #plantnutrition #probiotics #psychobiotics

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Connection found between anti-obesity statin drugs & gut Bacteroides 2

May
27
thread
According to a May 06 2020 Nature article, statin drugs, a common medication for lowering cholesterol, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that lower risk of cardiovascular disease. They are the most common cholesterol-lowering drugs, able to reduce illness and mortality, according to Wikipedia.

The study referenced in the Nature article analyses human faecal samples, and classifies them into one of four groups called enterotypes, depending on the abundance of particular microbial species. These groupings are termed Bacteroides 1 (Bact1), Bacteroides 2 (Bact2), Ruminococcaceae (Rum) and Prevotella (Prev). Bacteroides 2 are associated with inflammation, and more Bacteroides bacteria than Faecalibacterium microbes.

The authors unexpectedly discovered that there were significantly fewer of the Bact2 enterotype than expected in obese individuals who were taking cholesterol-lowering drugs called statins. The authors found a connection between these gut microbes and the statin drugs, but further research is needed to determine the nature of that connection. According to the article, "molecules such as trimethylamine oxide, which are made by gut bacteria, might accelerate atherosclerosis, and their presence is associated with adverse cardiovascular outcomes, including death."

And study in the European Union called the MetaCardis project (http://www.metacardis.net) including nearly 900 participants whose data they analysed, also found a higher prevalence of the Bact2 enterotype with a higher body-mass index and obesity.

See article, https://www.nature.com/articles/d41586-020-01281-0 .
#ai #bacteria #cardiovasculardisease #datascience #gutmicrobiome #health #healthinnovation #healthtech #obesity

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Three Classical Text of Ayurveda

May
24
thread
Three Classical Text of Ayurveda
There are three main classical text of Ayurveda:

1) Charaka Samhita - is the book of internal medicine and includes the eight systems of the body. This also comprises the basic concepts of Ayurveda, the Ayurvedic School of Physicians.

2) Sushruta Samhita - is the book of surgery. This book includes detailed description of surgical instruments and what they are used for, not only surgical instruments familiar to the west, but also eastern instruments such as needles for Chinese acupuncture, for example.

3) Ashtanga Sanraha & Ashtaga Hyridayam - The Hridayam over 7,500 verses, is written in poetry and prose. Both works have been dated about the same time and are believed to come after the Charaka Samhita and Sushruta Samhita. It outlines the sub kapha doshas for the first time with emphasis on treating the physical body.

More information about the Ayurveda classical text is available at The Ayurveda Institute, https://www.ayurveda.com/resources/articles/the-ancient-ayurvedic-writings
#Indianmedicine #ayurveda #bacteria #diet #easternmedicine #gutmicrobiome #health #herbalmedicine #herbs #plantnutrition #spices

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More links of gut microbiome to the brain

May
20
thread
Pavlov's classical conditioning... Pavlov's classical conditioning with dogs. source: Shutterstock
A May 17 2020 article in Neuroscience News published proceedings of the National Academy of Sciences, brings us more evidence of the brain-body connection. If you took psychology classes in college you are familiar with Ivan Pavlov's stimulus- response tests on dogs. Since his revolutionary research back in the mid- 1800s, this has come to be known as "classical conditioning". The brain-gut connection dates back to Pavlov's work. Peter Strick director at the University of Pittsburgh Brain Institute, is quoted in the article referring to Pavlov's famous research that the "central nervous system uses environmental signals and past experience to generate anticipatory responses that promote efficient digestion."

Dr. Strick and his associate Dr. David Levintha, professor of gastroenterology at Pitt, were able to trace the connection of signals between the gut and brain's rostral insula in mice confirming the connection of one's emotional, past experiences and contextual knowledge to the gut.

A January 29, 2020 article on Nature.com points to a couple of studies that suggest there is another connection between our gut microbiome and autism.

John Cryan, a biochemist at University College Cork in Ireland, was among the first researchers to investigate how gut microbes affect social behaviour. In 2014, he reported that germ-free mice — those lacking the typical mix of gut microbes — avoided other mice, shunned new social situations and groomed themselves excessively. “It started to crystallize that the microbiome was involved in many aspects of behaviour,” Cryan says.

Clostridia bacterial pathogens, for instance, generate propionic acid in the gut — a short-chain fatty acid known to disrupt the production of neurotransmitters. Propionic acid also causes autism-like symptoms in rats.

Deficits in beneficial gut bacteria might also affect social brain function. In 2017, Cryan reported that when mice with an autism-like condition had lower levels of Bifidobacterium and Blautia gut bacteria, their guts made less tryptophan and bile acid — compounds needed to produce serotonin3. And children with autism have been consistently found to have lower levels of Veillonellaceae, Coprococcus and Prevotella gut bacteria.

(Source: https://neurosciencenews.com/gut-brain-connection-16416/amp/ , and https://www.nature.com/articles/d41586-020-00198-y ).

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